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Evaluation and Treatment of Depression in Stroke Patients: A Systematic Review
Randomized controlled trials (RCTs), observational studies, systematic reviews, review articles, case reports, clinical studies, and meta-analyses were included in the research, which covered post-stroke depression patients and how to identify and treat them. There were 545 possibly related titles found in the database search. Finally, each ...
Poststroke Depression: A Scientific Statement for Healthcare
Depression is common after stroke, affecting approximately one third of stroke survivors at any one time after stroke (compared with 5%-13% of adults without stroke), with a cumulative incidence of 55%. 4 - 6 Hackett et al performed a systematic review and meta-analysis of 51 studies conducted before June 2004 and revealed a pooled frequency estimate of PSD of 33% (95% confidence interval ...
The overlap between poststroke and vascular depression: A case study
Poststroke depression (PSD) has been defined as "depression occurring in the context of a clinically apparent stroke as opposed to silent CVD.". [ 1] PSD has been found in about 25%-50% of patients with stroke; about half of them have major depressive disorders. [ 1, 2, 3] Depression is largely thought to be a direct consequence of the ...
Depression, Anxiety, and Suicide After Stroke: A Narrative Review of
Depression and anxiety each affect around 1 in 3 people during the first year after a stroke. Suicide causes the death of about 3 to 4/1000 stroke survivors during the first 5 years. This narrative review describes the best available evidence for the epidemiology of depression, anxiety, and suicide; their prevention; and the treatment of anxiety and depression. We conclude with directions for ...
The advances of post-stroke depression: 2021 update
Post-stroke depression (PSD) is one of common and serious sequelae of stroke. Approximately, one in three stroke survivors suffered from depression after stroke. It heavily affected functional rehabilitation, which leaded to poor quality of life. What is worse, it is strongly associated with high mortality. In this review, we aimed to derive a comprehensive and integrated understanding of PSD ...
Post-Stroke Depression: A Review
Poststroke depression (PSD) has been recognized by psychiatrists for more than 100 years, but controlled systematic studies did not begin until the 1970s. Meta-analyses addressing almost all major clinical issues in the field have emerged because of the relatively small number of patients included in some stroke studies. In order to build large databases, these meta-analyses have merged ...
Post-stroke depression: A 2020 updated review
Abstract. Background: Post-stroke depression (PSD) is common and associated with higher mortality, poorer recovery, more pronounced cognitive deficits, and lower quality of life than is stroke without depression. This manuscript will conduct an updated, comprehensive and clinically-useful review of the risk factors, pathophysiology, assessment ...
Management of Depression After Stroke
Abstract. Background and Purpose— Although depression may affect recovery and outcome after stroke, it is often overlooked or inadequately managed, and there is uncertainty regarding the benefits of antidepressant therapy in this setting. We aimed to assess the effectiveness of antidepressants for the treatment and prevention of depression ...
Prevalence and natural history of depression after stroke: A ...
Prevalence of depression after stroke. A total of 77 studies ... There was no great difference in pooled prevalence of depression across method of case selection. The pooled estimates for the 62 studies that included people with both ischemic stroke and haemorrhagic stroke was 29% (95% CI 26 to 32); for the 24 studies that included people with ...
Post-stroke depression: A 2020 updated review
1. Background/introduction. Depression and cerebrovascular accident (stroke) are two major causes of socioeconomic burden. The World Health Organization (WHO) recently reported that depression "is the leading cause of disability worldwide" [1], while stroke usually ranks among the top three causes of disease burden [2, 3].A meta-analysis of 119 population-based studies (fifty-eight from ...
Post-stroke emotionalism: Diagnosis, pathophysiology, and treatment
Pooled estimates from a single systematic review and recent single other longitudinal cohort study suggest PSE affects approximately one in five stroke survivors 6 months after stroke and at least one in 8 up to 12 months, 4,21 although recruitment biases overestimating prevalence are likely in those studies not deploying consecutive ...
Association between post-stroke depression and functional outcomes: A
Background Post-stroke depression (PSD) is a frequent problem in stroke patients, affecting their rehabilitation process and functional outcomes. Several studies have investigated the relationship between PSD and functional outcomes, but the results have been inconsistent. Objective This systematic review of non-experimental studies aims to investigate the prevalence of post-stroke depression ...
A sudden and severe depressive episode after a left cingulate gyrus
The pathophysiology of post-stroke depression is not yet clearly defined, but studies suggest contributions from both psychosocial factors and stroke-related factors, such as lesions affecting the frontal-subcortical circuits. Early treatment has a positive impact on post-stroke rehabilitation outcome and survival.
Post-stroke depression: the case for augmented, individually tailored
Abstract. In this review, we begin by considering why post-stroke depression (PSD) is so prevalent. We then examine the current evidence base to support cognitive behavioural therapy (CBT) as a treatment approach for the condition. While there is limited evidence currently, we demonstrate that much remains to be established with regard to PSD ...
Prevalence and natural history of depression after stroke: A systematic
Prevalence of depression after stroke. A total of 77 studies ... There was no great difference in pooled prevalence of depression across method of case selection. The pooled estimates for the 62 studies that included people with both ischemic stroke and haemorrhagic stroke was 29% (95% CI 26 to 32); for the 24 studies that included people with ...
Determinants of post-stroke depression among stroke survivors at
Stroke is one of the most common causes of disability among adults. Post-stroke depression (PSD) is a frequent neuropsychiatric complication in stroke patients. Despite the increasing prevalence of stroke, there is a paucity of data on PSD and its determinants among stroke survivors in developing countries like Ethiopia. We aim to assess the factors associated with PSD in survivors of stroke.
Post-stroke Depression Increases Disability More Than 15% in Ischemic
Introduction. Post-stroke depression (PSD) is one of the most frequent neuropsychiatric consequences of stroke. It affects almost 30% of stroke survivors (), and thus may greatly influence the prognosis, not only "quoad valetudinem" (of health) but also "quoad vitam" (of life).In fact, patients with PSD have an increased risk of mortality (have an increased risk of mortality, both ...
Care Management of Poststroke Depression
Methods— We conducted a prospective, randomized, outcome-blinded trial in 188 ischemic stroke survivors identified at the time of admission to one of 4 Indianapolis hospitals. Depression screening and enrollment occurred between 1 and 2 months poststroke. The Activate-Initiate-Monitor intervention was a care management program that included A ...
AHA Issues Statement on Nursing's Role in Psychosocial Health Post-Stroke
A literature search was performed for studies on psychological health in stroke from 2018 to 2023, which were reviewed by an AHA writing group. Patients who have poststroke depression may have impaired executive functioning, problem-solving, psychomotor speed, attention, and memory, and AHA stroke guidelines recommend routine depression ...
Post-stroke Depression Increases Disability More Than 15% in ...
We performed a retrospective, case-control study in consecutive ischemic stroke patients admitted to our stroke rehabilitation unit. Patients were matched for severity of neurological impairment (evaluated with the Canadian Neurological Scale, CNS), age (difference within 1 year), and onset admissio …
The importance of lesion location in poststroke depression: A critical
Mood disorder may be a specific complication of stroke. An earlier finding of an association between left anterior lesions and poststroke depression stimulated interest in the significance of stroke lesion characteristics. Subsequent research efforts, however, often failed to replicate this finding. This paper represents a critical appraisal of hemispheric lesion localization studies by CT ...
Understanding Why Post-Stroke Depression May Be the Norm Rather Than
Post-stroke depression (PSD) is a major driver for poor recovery, negative quality of life, poor rehabilitation outcomes and poor functional ability. ... Moreover, a case control study comparing stroke survivors with and without depression has also provided evidence that the presence of mutations in the 5-HTTLPR gene resulted in a three-fold ...
Suppression of neuronal CDK9/p53/VDAC signaling provides ...
Bioenergy decline occurs with reperfusion following acute ischemic stroke. However, the molecular mechanisms that limit energy metabolism and their impact on post-stroke cognitive and emotional complications are still unclear. In the present study, we demonstrate that the p53 transcriptional response is responsible for neuronal adenosine triphosphate (ATP) deficiency and progressively ...
Poststroke Cognitive Impairment and the Risk of Recurrent Stroke and
The American Heart Association and the American Stroke Association define poststroke cognitive impairment (PSCI) as all neurological disorders resulting from an overt stroke ranging from mild cognitive impairment to dementia. 1, 2 PSCI occurs in up to 60% of survivors of stroke in the first year after stroke. 2 Despite almost 30 years of research, the reported risks of stroke recurrence and ...
Impact of anxiety and depression on medication adherence ...
Psychological distress is common in patients with chronic medical conditions. However, it remains unclear whether the mechanisms explain the interaction between psychological distress and risk or protective factors for medication adherence are the same or different among individuals diagnosed with asthma and those who have survived a stroke. This study investigated the impact of anxiety and ...
Post-stroke depression, antidepressant treatment and rehabilitation
The aim of this study was to assess the specific influence of poststroke depression (PSD) on both basal functional status and rehabilitation results. We performed a case-control study in 290 stroke inpatients, matched for age (+/-1 year) and onset admission interval (+/-3 days) and divided in two groups according to the presence (PSD+) or ...
The effect of computerized cognitive training and transcranial direct
Background Working memory (WM) impairment is a common phenomenon after stroke; however, its management in rehabilitation is less researched. This systematic review and meta-analysis aimed to provide a quantitative synthesis of the impact of computerised cognitive training (CCT) and transcranial direct current stimulation (tDCS) on WM span in post-stroke individuals. Methods The literature ...
Epidemiology and treatment of post-stroke depression
Abstract. Mood depression is a common and serious complication after stroke. According to epidemiological studies, nearly 30% of stroke patients develop depression, either in the early or in the late stages after stroke. Although depression may affect functional recovery and quality of life after stroke, such condition is often ignored.
Predictors of Depression after Stroke
depression after stroke (Figure 1). Most studies excluded patients with subarachnoid hemorrhage, transient ischemic attack, and communication difficulties (eg, aphasia, confu-sion, or dementia). The multivariate models were developed on between 4422 and 13 99917 patients. A variety of methods were used to diagnose depression and assess the ...
IMAGES
VIDEO
COMMENTS
Randomized controlled trials (RCTs), observational studies, systematic reviews, review articles, case reports, clinical studies, and meta-analyses were included in the research, which covered post-stroke depression patients and how to identify and treat them. There were 545 possibly related titles found in the database search. Finally, each ...
Depression is common after stroke, affecting approximately one third of stroke survivors at any one time after stroke (compared with 5%-13% of adults without stroke), with a cumulative incidence of 55%. 4 - 6 Hackett et al performed a systematic review and meta-analysis of 51 studies conducted before June 2004 and revealed a pooled frequency estimate of PSD of 33% (95% confidence interval ...
Poststroke depression (PSD) has been defined as "depression occurring in the context of a clinically apparent stroke as opposed to silent CVD.". [ 1] PSD has been found in about 25%-50% of patients with stroke; about half of them have major depressive disorders. [ 1, 2, 3] Depression is largely thought to be a direct consequence of the ...
Depression and anxiety each affect around 1 in 3 people during the first year after a stroke. Suicide causes the death of about 3 to 4/1000 stroke survivors during the first 5 years. This narrative review describes the best available evidence for the epidemiology of depression, anxiety, and suicide; their prevention; and the treatment of anxiety and depression. We conclude with directions for ...
Post-stroke depression (PSD) is one of common and serious sequelae of stroke. Approximately, one in three stroke survivors suffered from depression after stroke. It heavily affected functional rehabilitation, which leaded to poor quality of life. What is worse, it is strongly associated with high mortality. In this review, we aimed to derive a comprehensive and integrated understanding of PSD ...
Poststroke depression (PSD) has been recognized by psychiatrists for more than 100 years, but controlled systematic studies did not begin until the 1970s. Meta-analyses addressing almost all major clinical issues in the field have emerged because of the relatively small number of patients included in some stroke studies. In order to build large databases, these meta-analyses have merged ...
Abstract. Background: Post-stroke depression (PSD) is common and associated with higher mortality, poorer recovery, more pronounced cognitive deficits, and lower quality of life than is stroke without depression. This manuscript will conduct an updated, comprehensive and clinically-useful review of the risk factors, pathophysiology, assessment ...
Abstract. Background and Purpose— Although depression may affect recovery and outcome after stroke, it is often overlooked or inadequately managed, and there is uncertainty regarding the benefits of antidepressant therapy in this setting. We aimed to assess the effectiveness of antidepressants for the treatment and prevention of depression ...
Prevalence of depression after stroke. A total of 77 studies ... There was no great difference in pooled prevalence of depression across method of case selection. The pooled estimates for the 62 studies that included people with both ischemic stroke and haemorrhagic stroke was 29% (95% CI 26 to 32); for the 24 studies that included people with ...
1. Background/introduction. Depression and cerebrovascular accident (stroke) are two major causes of socioeconomic burden. The World Health Organization (WHO) recently reported that depression "is the leading cause of disability worldwide" [1], while stroke usually ranks among the top three causes of disease burden [2, 3].A meta-analysis of 119 population-based studies (fifty-eight from ...
Pooled estimates from a single systematic review and recent single other longitudinal cohort study suggest PSE affects approximately one in five stroke survivors 6 months after stroke and at least one in 8 up to 12 months, 4,21 although recruitment biases overestimating prevalence are likely in those studies not deploying consecutive ...
Background Post-stroke depression (PSD) is a frequent problem in stroke patients, affecting their rehabilitation process and functional outcomes. Several studies have investigated the relationship between PSD and functional outcomes, but the results have been inconsistent. Objective This systematic review of non-experimental studies aims to investigate the prevalence of post-stroke depression ...
The pathophysiology of post-stroke depression is not yet clearly defined, but studies suggest contributions from both psychosocial factors and stroke-related factors, such as lesions affecting the frontal-subcortical circuits. Early treatment has a positive impact on post-stroke rehabilitation outcome and survival.
Abstract. In this review, we begin by considering why post-stroke depression (PSD) is so prevalent. We then examine the current evidence base to support cognitive behavioural therapy (CBT) as a treatment approach for the condition. While there is limited evidence currently, we demonstrate that much remains to be established with regard to PSD ...
Prevalence of depression after stroke. A total of 77 studies ... There was no great difference in pooled prevalence of depression across method of case selection. The pooled estimates for the 62 studies that included people with both ischemic stroke and haemorrhagic stroke was 29% (95% CI 26 to 32); for the 24 studies that included people with ...
Stroke is one of the most common causes of disability among adults. Post-stroke depression (PSD) is a frequent neuropsychiatric complication in stroke patients. Despite the increasing prevalence of stroke, there is a paucity of data on PSD and its determinants among stroke survivors in developing countries like Ethiopia. We aim to assess the factors associated with PSD in survivors of stroke.
Introduction. Post-stroke depression (PSD) is one of the most frequent neuropsychiatric consequences of stroke. It affects almost 30% of stroke survivors (), and thus may greatly influence the prognosis, not only "quoad valetudinem" (of health) but also "quoad vitam" (of life).In fact, patients with PSD have an increased risk of mortality (have an increased risk of mortality, both ...
Methods— We conducted a prospective, randomized, outcome-blinded trial in 188 ischemic stroke survivors identified at the time of admission to one of 4 Indianapolis hospitals. Depression screening and enrollment occurred between 1 and 2 months poststroke. The Activate-Initiate-Monitor intervention was a care management program that included A ...
A literature search was performed for studies on psychological health in stroke from 2018 to 2023, which were reviewed by an AHA writing group. Patients who have poststroke depression may have impaired executive functioning, problem-solving, psychomotor speed, attention, and memory, and AHA stroke guidelines recommend routine depression ...
We performed a retrospective, case-control study in consecutive ischemic stroke patients admitted to our stroke rehabilitation unit. Patients were matched for severity of neurological impairment (evaluated with the Canadian Neurological Scale, CNS), age (difference within 1 year), and onset admissio …
Mood disorder may be a specific complication of stroke. An earlier finding of an association between left anterior lesions and poststroke depression stimulated interest in the significance of stroke lesion characteristics. Subsequent research efforts, however, often failed to replicate this finding. This paper represents a critical appraisal of hemispheric lesion localization studies by CT ...
Post-stroke depression (PSD) is a major driver for poor recovery, negative quality of life, poor rehabilitation outcomes and poor functional ability. ... Moreover, a case control study comparing stroke survivors with and without depression has also provided evidence that the presence of mutations in the 5-HTTLPR gene resulted in a three-fold ...
Bioenergy decline occurs with reperfusion following acute ischemic stroke. However, the molecular mechanisms that limit energy metabolism and their impact on post-stroke cognitive and emotional complications are still unclear. In the present study, we demonstrate that the p53 transcriptional response is responsible for neuronal adenosine triphosphate (ATP) deficiency and progressively ...
The American Heart Association and the American Stroke Association define poststroke cognitive impairment (PSCI) as all neurological disorders resulting from an overt stroke ranging from mild cognitive impairment to dementia. 1, 2 PSCI occurs in up to 60% of survivors of stroke in the first year after stroke. 2 Despite almost 30 years of research, the reported risks of stroke recurrence and ...
Psychological distress is common in patients with chronic medical conditions. However, it remains unclear whether the mechanisms explain the interaction between psychological distress and risk or protective factors for medication adherence are the same or different among individuals diagnosed with asthma and those who have survived a stroke. This study investigated the impact of anxiety and ...
The aim of this study was to assess the specific influence of poststroke depression (PSD) on both basal functional status and rehabilitation results. We performed a case-control study in 290 stroke inpatients, matched for age (+/-1 year) and onset admission interval (+/-3 days) and divided in two groups according to the presence (PSD+) or ...
Background Working memory (WM) impairment is a common phenomenon after stroke; however, its management in rehabilitation is less researched. This systematic review and meta-analysis aimed to provide a quantitative synthesis of the impact of computerised cognitive training (CCT) and transcranial direct current stimulation (tDCS) on WM span in post-stroke individuals. Methods The literature ...
Abstract. Mood depression is a common and serious complication after stroke. According to epidemiological studies, nearly 30% of stroke patients develop depression, either in the early or in the late stages after stroke. Although depression may affect functional recovery and quality of life after stroke, such condition is often ignored.
depression after stroke (Figure 1). Most studies excluded patients with subarachnoid hemorrhage, transient ischemic attack, and communication difficulties (eg, aphasia, confu-sion, or dementia). The multivariate models were developed on between 4422 and 13 99917 patients. A variety of methods were used to diagnose depression and assess the ...